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Recombinant PTEN Monoclonal Antibody (AGEL8574)

Datasheet MSDS
SKU AGEL8574
Product Type Antibody
Reactivity Human, Mouse, Rat
Applications WB
Host Species Rabbit
Clonality Monoclonal
Clone C133269
Conjugate Unconjugated
$461 - $632

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Description

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Recombinant PTEN Monoclonal Antibody

The Recombinant PTEN Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C133269) against PTEN. PTEN (also designated MMAC1), products of tumor suppressor genes, are found deleted in most human gliomas. The PTEN genes are also mutated in many other tumors, such as brain, breast, kidney and prostate cancers. PTEN is a protein tyrosine phosphatase that may terminate the signaling transduction pathways mediated by PI 3-kinase/Akt. Produced by recombinant technology in Rabbit hosts and purified by affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.

This antibody is suitable for WB applications. It has been validated by WB analysis of K562, C6, 3T3, Hela. The target is localized to the Secreted. May be secreted via a classical signal peptide and reenter into cells with the help of a poly-Arg motif and Cytoplasm. Nucleus. Nucleus, PML body. Monoubiquitinated form is nuclear. Nonubiquitinated form is cytoplasmic. Colocalized with PML and USP7 in PML nuclear bodies. XIAP/BIRC4 promotes its nuclear localization.

Product Name:Recombinant PTEN Monoclonal Antibody
SKU:AGEL8574
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:10q23del, 4, 5-trisphosphate 3-ph, 5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, BZS, DEC, GLM2, MGC11227, MHAM, MMAC1, MMAC1 phosphatase and tensin homolog deleted on chromosome 10, Mutated in multiple advanced cancers 1, Phosphatase and tensin homolog, Phosphatase and tensin like protein, Phosphatidylinositol 3, Pten, PTEN1, TEP1
Reactivity:Human, Mouse, Rat
Immunogen:A synthetic peptide of human PTEN
Applications:WB
Clonality:Recombinant Monoclonal
Clone No:C133269
Host:Rabbit
Isotype:Rabbit IgG
Target:PTEN
Conjugation:Unconjugated
Observed MW:54 kDa
Calculated MW:47 kDa
Recommended Dilution:WB 1:500-1000
UniProt:P60484
Purification:Affinity purification
Concentration:0.3 mg/mL
Buffer:50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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