The Recombinant PU.1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C111267) against PU.1. Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF and ELISA applications. It has been validated by WB analysis of RAW264.7, Daudi and IHC analysis of Human tonsil, Mouse lung. The target is localized to the nucleus.
