The Recombinant PAI-1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110907) against PAI-1. This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF, IP and ELISA applications. It has been validated by IHC analysis of Human kidney. The target is localized to the secreted.
Product Name:
Recombinant PAI-1 Monoclonal Antibody
SKU:
AGEL6213
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
Clade E, Endothelial plasminogen activator inhibitor, Nexin, PAI, PAI 1, PAI-1, PAI1, PLANH, PLANH1, Plasminogen activator inhibitor, Plasminogen activator inhibitor 1, Plasminogen activator inhibitor type 1, Serine (or cysteine) proteinase inhibitor, Serine (or cysteine) proteinase inhibitor clade E (nexin plasminogen activator inhibitor type 1) member 1, Serpin E, Serpin E1, Serpin peptidase inhibitor clade E, Serpin peptidase inhibitor clade E (nexin plasminogen activator inhibitor type 1) member 1, SERPINE, Serpine 1, SERPINE1
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant Human PAI-1 protein
Applications:
WBIHCIFIPELISA
Clonality:
Recombinant Monoclonal
Clone No:
C110907
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
PAI-1
Conjugation:
Unconjugated
Recommended Dilution:
IHC 1:200-1000; WB 1:2000-10000; IF 1:200-1000; ELISA 1:5000-20000; IP 1:50-200
UniProt:
P05121
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
