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Key Features

Recombinant Rab8A Monoclonal Antibody (AGEL6849)

SKU AGEL6849
Product Type Antibody
Reactivity Human, Mouse, Rat
Applications WB, IHC-P, ICC/IF, FC
Host Species Rabbit
Clonality Monoclonal
Clone C111544
Conjugate Unconjugated
$606 - $843

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Description

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Recombinant Rab8A Monoclonal Antibody

The Recombinant Rab8A Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C111544) against Rab8A. The Rab8 GTPase is a member of the Ras superfamily that functions in protein transport and membrane restructuring. RAB8 has two isoforms, RAB8A and RAB8B, that share 40% amino acid identity in the C-terminal variable region. RAB8 activity is regulated by specific guanine nucleotide exchange factors (GEFs), that mediate GTP loading, and GTPase activating proteins (GAPs) that convert them into the inactive GDP-bound form. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.

This antibody is suitable for WB, IHC-P, ICC/IF and FC applications. It has been validated by WB analysis of K562, C6, 3T3, HeLa, MCF-7, SW620, IHC analysis of Human colon and IF analysis of HeLa, A549. The target is localized to the cell membrane, cytoplasm.

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