The Recombinant Rab8A Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C111544) against Rab8A. The Rab8 GTPase is a member of the Ras superfamily that functions in protein transport and membrane restructuring. RAB8 has two isoforms, RAB8A and RAB8B, that share 40% amino acid identity in the C-terminal variable region. RAB8 activity is regulated by specific guanine nucleotide exchange factors (GEFs), that mediate GTP loading, and GTPase activating proteins (GAPs) that convert them into the inactive GDP-bound form. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC-P, ICC/IF and FC applications. It has been validated by WB analysis of K562, C6, 3T3, HeLa, MCF-7, SW620, IHC analysis of Human colon and IF analysis of HeLa, A549. The target is localized to the cell membrane, cytoplasm.
Product Name:
Recombinant Rab8A Monoclonal Antibody
SKU:
AGEL6849
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
AA409338, MEL, Mel transforming oncogene, Mel transforming oncogene (derived from cell line NK14), Mel transforming oncogene (derived from cell line NK14) RAB8 homolog, Mel transforming oncogene (RAB8 homolog), MGC124948, Oncogene c mel, Oncogene c-mel, RAB, RAB8, RAB8A, RAB8A member RAS oncogene family, Ras associated protein RAB8, Ras related protein Rab 8A, Ras-related protein Rab-8A