The Recombinant RIP Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C310710) against RIP. ATP + a protein = ADP + a phosphoprotein., Promotes apoptosis and activation of NF-kappa-B. Required for TNFRSF1A mediated activation of NF-kappa-B., PTM:Autophosphorylated on serine and threonine residues., PTM:Proteolytically cleaved by caspase-8 during TNF-induced apoptosis. Cleavage abolishes NF-kappa-B activation and enhances pro-apototic signaling through the TRADD-FADD interaction., similarity:Belongs to the protein kinase superfamily. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB, IHC, IF and ELISA applications. It has been validated by WB analysis of HEK293 and IHC analysis of Rat kidney tissue, Human cervical cancer tissue. The target is localized to the cytoplasmic, membranous.
Product Name:
Recombinant RIP Monoclonal Antibody
SKU:
AGEL6019
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
Cell death protein RIP, FLJ39204, OTTHUMP00000039163, Receptor (TNFRSF) interacting serine threonine kinase 1, Receptor interacting protein, receptor interacting protein 1, Receptor interacting protein kinase 1, Receptor interacting serine threonine protein kinase 1, Receptor TNFRSF interacting serine threonine kinase 1, Receptor-interacting protein 1, Receptor-interacting serine/threonine-protein kinase 1, Rinp, RIP, RIP 1, RIP-1, RIP1, RIPK, RIPK 1, RIPK1, Serine threonine protein kinase RIP, Serine/threonine-protein kinase RIP
Reactivity:
Human
Immunogen:
Recombinant Human RIP protein
Applications:
WBIHCIFELISA
Clonality:
Recombinant Monoclonal
Clone No:
C310710
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
RIP
Conjugation:
Unconjugated
Observed MW:
76 kDa
Calculated MW:
76 kDa
Recommended Dilution:
IHC 1:200-1000; WB 1:1000-5000; IF 1:200-1000; ELISA 1:5000-20000
UniProt:
Q13546
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
