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Key Features

Recombinant ROCK1 Monoclonal Antibody (AGEL5937)

SKU AGEL5937
Product Type Antibody
Reactivity Human, Mouse, Rat
Applications WB, IHC, IF, IP, ELISA
Host Species Rabbit
Clonality Monoclonal
Clone C110625
Conjugate Unconjugated
€409 - €559

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Description

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Recombinant ROCK1 Monoclonal Antibody

The Recombinant ROCK1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110625) against ROCK1. This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.

This antibody is suitable for WB, IHC, IF, IP and ELISA applications. It has been validated by WB analysis of C6 and IHC analysis of Human testis tissue. The target is localized to the cytoplasm, membrane.

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