The Recombinant RSK3 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110868) against RSK3. ATP + a protein = ADP + a phosphoprotein., cofactor:Magnesium., enzyme regulation:Activated by multiple phosphorylations on threonine and serine residues., Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB., PTM:Autophosphorylated on Ser-377, as part of the activation process., similarity:Belongs to the protein kinase superfamily., similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily., similarity:Contains 1 AGC-kinase C-terminal domain., similarity:Contains 2 protein kinase domains., subunit:Forms a complex with either ERK1 or ERK2 in quiescent cells. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF, IP and ELISA applications. It has been validated by IHC analysis of Human lung cancer. The target is localized to the nucleus, cytoplasm.
Product Name:
Recombinant RSK3 Monoclonal Antibody
SKU:
AGEL6174
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
90 kDa ribosomal protein S6 kinase 2, 90kDa, HU 2, HU-2, KS6A2, MAP kinase activated protein kinase 1c, MAP kinase-activated protein kinase 1c, MAPK-activated protein kinase 1c, MAPKAP kinase 1c, MAPKAPK-1c, MAPKAPK1C, Mitogen.activated protein kinase-activated protein kinase 1C, p90 RSK3, p90-RSK, p90-RSK 2, p90-RSK3, p90RSK, p90RSK2, polypeptide 2, pp90RSK, pp90RSK3, ribosomal protein S6 kinase, Ribosomal protein S6 kinase alpha-2, Ribosomal S6 kinase 3, RPS6KA, RPS6KA2, RSK, RSK 3, RSK-3, RSK3, S6K alpha, S6K alpha 2, S6K-alpha, S6K-alpha-2, S6K-alpha2
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant Human RSK3 protein
Applications:
WBIHCIFIPELISA
Clonality:
Recombinant Monoclonal
Clone No:
C110868
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
RSK3
Conjugation:
Unconjugated
Recommended Dilution:
IHC 1:200-1000; WB 1:2000-10000; IF 1:200-1000; ELISA 1:5000-20000; IP 1:50-200
UniProt:
Q15349
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.