The Recombinant RXRA Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C371564) against RXRA. Retinoid X receptor α (RXRA) is the founding RXR family member and is predominantly expressed in the liver, kidney, epidermis, intestine, and a variety of tissues. Knockout of the murine rxrα gene results in embryonic lethality tentatively due to myocardial hypoplasia, which demonstrates the importance of RXRA in retinoid signaling in vivo. Biochemical evidence suggests that RXRA transcriptional activity is post-translationally regulated through the Ras-Raf-MAPK signaling cascade. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB and IF applications. It has been validated by WB analysis of HeLa, MCF-7 and IF analysis of MCF-7. The target is localized to the mitochondrion, nucleus, cytoplasm.
Product Name:
Recombinant RXRA Monoclonal Antibody
SKU:
AGEL6869
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
NR2B, NR2B1, Retinoid X receptor alpha, RXRA
Reactivity:
Human
Immunogen:
Recombinant human RXRA fragment
Applications:
WBIF
Clonality:
Recombinant Monoclonal
Clone No:
C371564
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
RXRA
Conjugation:
Unconjugated
Observed MW:
56 kDa
Calculated MW:
51 kDa
Recommended Dilution:
WB 1:1000; IF 1:50
UniProt:
P19793
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
