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Key Features

Recombinant SATB1 Monoclonal Antibody (AGEL6580)

Datasheet MSDS
SKU AGEL6580
Product Type Antibody
Reactivity Human
Applications WB, IHC, FCM
Host Species Rabbit
Clonality Monoclonal
Clone C321275
Conjugate Unconjugated
$606 - $843

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Description

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Recombinant SATB1 Monoclonal Antibody

The Recombinant SATB1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C321275) against SATB1. Crucial silencing factor contributing to the initiation of X inactivation mediated by Xist RNA that occurs during embryogenesis and in lymphoma. Binds to DNA at special AT-rich sequences, the consensus SATB1-binding sequence (CSBS), at nuclear matrix- or scaffold-associated regions. Transcriptional repressor controlling nuclear and viral gene expression in a phosphorylated and acetylated status-dependent manner, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.

This antibody is suitable for WB, IHC and FCM applications. It has been validated by WB analysis of Jurkat, THP-1, IHC analysis of Human tonsil and FCM analysis of Jurkat. The target is localized to the nucleus.

Product Name:Recombinant SATB1 Monoclonal Antibody
SKU:AGEL6580
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:SATB, SATB1
Reactivity:Human
Immunogen:Recombinant human SATB1 fragment
Applications:WBIHCFCM
Clonality:Recombinant Monoclonal
Clone No:C321275
Host:Rabbit
Isotype:Rabbit IgG
Target:SATB1
Conjugation:Unconjugated
Observed MW:100 kDa
Calculated MW:86 kDa
Recommended Dilution:WB 1:500-2000; IHC 1:200-1000; FCM 1:50-100
UniProt:Q01826
Purification:Protein A
Concentration:1 mg/mL
Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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