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Recombinant SF3B1 Monoclonal Antibody (AGEL8601)

Datasheet MSDS
SKU AGEL8601
Product Type Antibody
Reactivity Human, Mouse, Hamster
Applications WB, IHC-P
Host Species Rabbit
Clonality Monoclonal
Clone C223296
Conjugate Unconjugated
$461 - $632

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Description

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Recombinant SF3B1 Monoclonal Antibody

The Recombinant SF3B1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C223296) against SF3B1. This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Produced by recombinant technology in Rabbit hosts and purified by affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Hamster samples.

This antibody is suitable for WB and IHC-P applications. It has been validated by WB analysis of Hela, CHO-K1, Ramos and IHC analysis of Human lung cancer. The target is localized to the Nucleus speckle. Note=During mitosis, transiently dispersed from the nuclear speckles to the cytoplasm.

Product Name:Recombinant SF3B1 Monoclonal Antibody
SKU:AGEL8601
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:Hsh155, MDS, PRP10, PRPF10, SAP155, SF3B1, SF3b155
Reactivity:Human, Mouse, Hamster
Immunogen:A synthetic peptide of human SF3B1
Applications:WBIHC-P
Clonality:Recombinant Monoclonal
Clone No:C223296
Host:Rabbit
Isotype:Rabbit IgG
Target:SF3B1
Conjugation:Unconjugated
Observed MW:146 kDa
Calculated MW:146 kDa
Recommended Dilution:WB 1:500-1000; IHC 1:50-100
UniProt:O75533
Purification:Affinity purification
Concentration:0.3 mg/mL
Buffer:50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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