The Recombinant SLC25A12 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C121560) against SLC25A12. The calcium-binding mitochondrial carrier protein (SLC25A12), also named as ARALAR or AGC1, is an aspartate-glutamate exchange protein responsible for transporting mitochondrial aspartate across the mitochondrial inner membrane in exchange for cytosolic glutamate. SLC25A12 and other proteins of the aspartate-glutamate carrier (AGC) group are required for the transfer of mitochondrial aspartate to the cytosol, a key step in urea synthesis. Research studies using SLC25A12-knockout mice indicate that SLC25A12 plays an important role in proper CNS myelination. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB and IHC applications. It has been validated by WB analysis of HeLa, Mouse skeletal muscle and IHC analysis of Mouse cardiac muscle, Rat cardiac muscle. The target is localized to the cytoplasm.
Product Name:
Recombinant SLC25A12 Monoclonal Antibody
SKU:
AGEL6865
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
AGC, AGC1, Araceli hiperlarga, ARALAR, ARALAR1, Calcium binding mitochondrial carrier superfamily member, Calcium binding mitochondrial carrier superfamily member Aralar1, Calcium-binding mitochondrial carrier protein Aralar1, CMC1, EIEE, EIEE39, member 12, Mitochondrial aspartate glutamate carrier 1, SLC25A, SLC25A12, solute carrier family 25, Solute carrier family 25 (aspartate/glutamate carrier) member 12, Solute carrier family 25 (mitochondrial carrier Aralar) member 12, Solute carrier family 25 member 12
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant human SLC25A12 fragment
Applications:
WBIHC
Clonality:
Recombinant Monoclonal
Clone No:
C121560
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
SLC25A12
Conjugation:
Unconjugated
Observed MW:
75 kDa
Calculated MW:
75 kDa
Recommended Dilution:
WB 1:2000-5000; IHC 1:50-100
UniProt:
O75746
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
Immunohistochemistry of paraffin-embedded Mouse cardiac muscle using SLC25A12 Monoclonal Antibody at dilution of 1:100.
Immunohistochemistry of paraffin-embedded Rat cardiac muscle using SLC25A12 Monoclonal Antibody at dilution of 1:100.
Western Blot with SLC25A12 Monoclonal Antibody at dilution of 1:5000. Lane 1: HeLa, Lane 2: Mouse skeletal muscle Observed-MW:75 kDa Calculated-MW:75 kDa
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