The Recombinant SLFN11 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C331492) against SLFN11. SLFN11 is a nuclear protein that belongs to the Schlafen (SLFN) family of genes involved in cell cycle regulation and growth inhibition. Expression of SLFN11 predicts sensitivity of cancer cell lines to DNA-damaging agents. Evidence suggests that in the presence of DNA-targeted therapies, SLFN11 is recruited to stressed replication forks where it blocks replication, leading to cell death. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB applications. It has been validated by WB analysis of K562 (Negative control), Jurkat, A431. The target is localized to the nucleus.
Product Name:
Recombinant SLFN11 Monoclonal Antibody
SKU:
AGEL6797
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
SLFN11, SLFN8/9
Reactivity:
Human
Immunogen:
Recombinant human SLFN11 fragment
Applications:
WB
Clonality:
Recombinant Monoclonal
Clone No:
C331492
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
SLFN11
Conjugation:
Unconjugated
Observed MW:
103 kDa
Calculated MW:
103 kDa
Recommended Dilution:
WB 1:500-1000
UniProt:
Q7Z7L1
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
