The Recombinant SMARCD2 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C121525) against SMARCD2. SMARCD2 is a member of the SWI/SNF family of proteins which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. It is part of the large ATP-dependent chromatin remodeling complex SNF/SWI. SMARCD2 is Critical regulator of myeloid differentiation, controlling granulocytopoiesis and the expression of genes involved in neutrophil granule formation. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC-P, FC and IP applications. It has been validated by WB analysis of HeLa, T24, C2C12. The target is localized to the nucleus.
WB 1:1000; IHC-P 1:100-200; IP 1:20-50; FCM 1:200-500
UniProt:
Q92925, Q99JR8, O54772
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
Western blot analysis of HeLa, T24 and C2C12 cell lysates using SMARCD2 Antibody (RMEA1525) at a dilution of 1:1000. Observed-MW:59 kDa Calculated-MW:59 kDa