The Recombinant Snail Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C171015) against Snail. The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IF, IP and ELISA applications. It has been validated by WB analysis of HeLa. The target is localized to the nucleus, cytoplasm, Once phosphorylated (probably on Ser-107, ser-111, Ser-115 and Ser-119) it is exported from the nucleus to the cytoplasm where subsequent phosphorylation of the destruction motif and ubiquitination involving BTRC occurs.
Product Name:
Recombinant Snail Monoclonal Antibody
SKU:
AGEL6321
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
dJ710H, dJ710H13.1, Drosophila, homolog of, Protein sna, Protein snail homolog, Protein snail homolog 1, SLUGH, SLUGH2, SNA, Sna protein, SNAH, SNAI, SNAI1, SNAIL, Snail 1 homolog, Snail 1 zinc finger protein, Snail family transcriptional repressor 1, Snail homolog 1 (Drosophila), SNAIL1, zinc finger protein SNAI, zinc finger protein SNAI1
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant Human Snail protein
Applications:
WBIFIPELISA
Clonality:
Recombinant Monoclonal
Clone No:
C171015
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
Snail
Conjugation:
Unconjugated
Observed MW:
29 kDa
Calculated MW:
29 kDa
Recommended Dilution:
WB 1:2000-10000; IF 1:200-1000; ELISA 1:5000-20000; IP 1:50-200
UniProt:
O95863
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
