The Recombinant SRSF2 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110898) against SRSF2. The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF, IP and ELISA applications. It has been validated by IHC analysis of Human cervical carcinoma. The target is localized to the nucleus, nucleus, nucleoplasm, nucleus speckle, Phosphorylation by SRPK2 provokes its redistribution from the nuclear speckle to nucleoplasm.
