The Recombinant STML2 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C170778) against STML2. Enables GTPase binding activity; T cell receptor binding activity; and cardiolipin binding activity. Involved in intracellular calcium ion homeostasis; mitochondrion organization; and protein complex oligomerization. Acts upstream of or within T cell receptor signaling pathway. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IF, IP and ELISA applications. It has been validated by WB analysis of K562. The target is localized to the cell membrane, peripheral membrane protein, mitochondrion, mitochondrion inner membrane, lipid-anchor, mitochondrion intermembrane space, membrane raft, cytoplasm, cytoskeleton, Behaves as an integral membrane protein of the mitochondrion despite the absence of a detectable transmembrane domain (PubMed:21746876). Also associates with the actin cytoskeleton and membrane rafts in activated T-cells (PubMed:18641330, PubMed:10713127). A minor pool is associated with the plasma membrane and is enriched at the immunological synapse in activated T-cells (PubMed:22623988).
Product Name:
Recombinant STML2 Monoclonal Antibody
SKU:
AGEL6085
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
EPB72 like protein, EPB72 like protein 2, EPB72-like protein 2, HSPC, HSPC108, mitochondrial, OTTHUMP, OTTHUMP00000021320, Paraprotein target, Paraprotein target 7, Paratarg 7, SLP, SLP 2, SLP-2, SLP2, STML2, STML2_HUMAN, Stomatin (EPB72) like, Stomatin (EPB72) like 2, Stomatin like, Stomatin like 2, Stomatin like protein, Stomatin like protein 2, Stomatin-like protein 2, STOML, STOML2
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant Human STML2 protein
Applications:
WBIFIPELISA
Clonality:
Recombinant Monoclonal
Clone No:
C170778
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
STML2
Conjugation:
Unconjugated
Observed MW:
39 kDa
Calculated MW:
39 kDa
Recommended Dilution:
WB 1:2000-10000; IF 1:200-1000; ELISA 1:5000-20000; IP 1:50-200
UniProt:
Q9UJZ1
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.