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Key Features

Recombinant STML2 Monoclonal Antibody (AGEL6085)

SKU AGEL6085
Product Type Antibody
Reactivity Human, Mouse, Rat
Applications WB, IF, IP, ELISA
Host Species Rabbit
Clonality Monoclonal
Clone C170778
Conjugate Unconjugated
$540 - $738

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Description

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Recombinant STML2 Monoclonal Antibody

The Recombinant STML2 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C170778) against STML2. Enables GTPase binding activity; T cell receptor binding activity; and cardiolipin binding activity. Involved in intracellular calcium ion homeostasis; mitochondrion organization; and protein complex oligomerization. Acts upstream of or within T cell receptor signaling pathway. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.

This antibody is suitable for WB, IF, IP and ELISA applications. It has been validated by WB analysis of K562. The target is localized to the cell membrane, peripheral membrane protein, mitochondrion, mitochondrion inner membrane, lipid-anchor, mitochondrion intermembrane space, membrane raft, cytoplasm, cytoskeleton, Behaves as an integral membrane protein of the mitochondrion despite the absence of a detectable transmembrane domain (PubMed:21746876). Also associates with the actin cytoskeleton and membrane rafts in activated T-cells (PubMed:18641330, PubMed:10713127). A minor pool is associated with the plasma membrane and is enriched at the immunological synapse in activated T-cells (PubMed:22623988).

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