The Recombinant Stromal Interaction Molecule 1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110616) against Stromal Interaction Molecule 1. This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF, IP and ELISA applications. It has been validated by WB analysis of C6 and IHC analysis of Human breast tissue. The target is localized to the membrane.
Recombinant Human Stromal Interaction Molecule 1 protein
Applications:
WBIHCIFIPELISA
Clonality:
Recombinant Monoclonal
Clone No:
C110616
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
Stromal Interaction Molecule 1
Conjugation:
Unconjugated
Observed MW:
77 kDa
Calculated MW:
77 kDa
Recommended Dilution:
IHC 1:200-1000; WB 1:1000-5000; IF 1:200-1000; ELISA 1:5000-20000; IP 1:50-200
UniProt:
Q13586
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
Immunohistochemistry of paraffin-embedded human breast tissue using Recombinant Stromal Interaction Molecule 1 Monoclonal Antibody at dilution of 1:200.
Western Blot with Recombinant Stromal Interaction Molecule 1 Monoclonal Antibody at dilution of 1:1000 dilution. Lane A: C6 cells. Observed-MW:77 kDa Calculated-MW:77 kDa