The Recombinant TGF beta 1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C121523) against TGF beta 1. Transforming growth factor-β (TGF-β) superfamily members are critical regulators of cell proliferation and differentiation, developmental patterning and morphogenesis, and disease pathogenesis. TGF-β elicits signaling through three cell surface receptors: type I (RI), type II (RII), and type III (RIII). Type I and type II receptors are serine/threonine kinases that form a heteromeric complex. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB and IHC-P applications. It has been validated by WB analysis of HeLa, A549, U-2 OS. The target is localized to the secreted.
