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Key Features

Recombinant Thyroglobulin Monoclonal Antibody (AGEL6603)

SKU AGEL6603
Product Type Antibody
Reactivity Human, Mouse, Rat
Applications WB, IHC, ICC/IF, FC
Host Species Rabbit
Clonality Monoclonal
Clone C111298
Conjugate Unconjugated
$606 - $843

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Description

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Recombinant Thyroglobulin Monoclonal Antibody

The Recombinant Thyroglobulin Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C111298) against Thyroglobulin. Acts as a substrate for the production of iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). The synthesis of T3 and T4 involves iodination of selected tyrosine residues of TG/thyroglobulin followed by their oxidative coupling in the thyroid follicle lumen. Following TG re-internalization and lysosomal-mediated proteolysis, T3 and T4 are released from the polypeptide backbone leading to their secretion into the bloodstream. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.

This antibody is suitable for WB, IHC, ICC/IF and FC applications. The target is localized to the extracellular region or secreted.

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