The Recombinant TLS/FUS Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110627) against TLS. This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF and ELISA applications. It has been validated by WB analysis of HepG2 and IHC analysis of Mouse brain tissue, Rat brain tissue. The target is localized to the nucleus.
Product Name:
Recombinant TLS/FUS Monoclonal Antibody
SKU:
AGEL5939
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
75 kDa DNA pairing protein, 75 kDa DNA-pairing protein, ALS, ALS6, Amyotrophic lateral sclerosis 6, ETM, ETM4, FUS, FUS CHOP, Fus like protein, FUS1, Fused in sarcoma, Fusion, Fusion derived from t, Fusion gene in myxoid liposarcoma, Heterogeneous nuclear ribonucleoprotein P2, hnRNP P2, HNRNPP, HNRNPP2, Oncogene FUS, Oncogene TLS, POMP, POMP75, RNA binding protein FUS, RNA-binding protein FUS, TLS, TLS CHOP, Translocated in liposarcoma, Translocated in liposarcoma protein
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant Human TLS/FUS protein
Applications:
WBIHCIFELISA
Clonality:
Recombinant Monoclonal
Clone No:
C110627
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
TLS
Conjugation:
Unconjugated
Observed MW:
70 kDa
Calculated MW:
53 kDa
Recommended Dilution:
IHC 1:500-2000; WB 1:500-2000; IF 1:200-1000; ELISA 1:5000-20000
UniProt:
P35637
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
Immunohistochemistry of paraffin-embedded mouse brain tissue using Recombinant TLS/FUS Monoclonal Antibody at dilution of 1:200.
Immunohistochemistry of paraffin-embedded rat brain tissue using Recombinant TLS/FUS Monoclonal Antibody at dilution of 1:200.
Western Blot with Recombinant TLS/FUS Monoclonal Antibody at dilution of 1:1000 dilution. Lane A: HepG2 cells. Observed-MW:70 kDa Calculated-MW:53 kDa