The Recombinant TOP3B Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C371595) against TOP3B. DNA topoisomerase 3-beta-1(TOP3B), an enzyme that controls and alters the topologic states of DNA during transcription. TOP3B catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. TOP3B interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB and IF applications. It has been validated by WB analysis of K562, Human heart and IF analysis of K-562. The target is localized to the nucleus.
Product Name:
Recombinant TOP3B Monoclonal Antibody
SKU:
AGEL6900
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
TOP3B, TOP3B1
Reactivity:
Human
Immunogen:
Peptide. This information is proprietary to PTMab
Applications:
WBIF
Clonality:
Recombinant Monoclonal
Clone No:
C371595
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
TOP3B
Conjugation:
Unconjugated
Observed MW:
97 kDa
Calculated MW:
97 kDa
Recommended Dilution:
WB 1:1000-2000; IF 1:100-200
UniProt:
O95985
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
