The Recombinant TRAF6 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110239) against TRAF6. The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from, members of the TNF receptor superfamily. This protein mediates signaling from members of the TNF receptor superfamily as well as the Toll/IL-1 family. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF and ELISA applications. It has been validated by WB analysis of HeLa, 293T, Jurkat, A431, K562. The target is localized to the cytoplasm, cytoplasm, cell cortex, nucleus, lipid droplet, Found in the nuclei of some aggressive B-cell lymphoma cell lines as well as in the nuclei of both resting and activated T- and B-lymphocytes. Found in punctate nuclear body protein complexes. Ubiquitination may occur in the cytoplasm and sumoylation in the nucleus. RSAD2/viperin recruits it to the lipid droplet (By similarity).
Product Name:
Recombinant TRAF6 Monoclonal Antibody
SKU:
AGEL5558
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
E3 ubiquitin protein ligase, E3 ubiquitin-protein ligase TRAF6, Interleukin 1 signal transducer, Interleukin-1 signal transducer, MGC, MGC 3310, MGC3310, MGC:3310, OTTHUMP00000232772, OTTHUMP00000232773, RING finger protein 85, RNF, RNF 85, RNF85, TNF receptor associated factor 6, TNF receptor-associated factor 6, TRAF, TRAF 6, TRAF6
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant Human TRAF6 protein
Applications:
WBIHCIFELISA
Clonality:
Recombinant Monoclonal
Clone No:
C110239
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
TRAF6
Conjugation:
Unconjugated
Observed MW:
60 kDa
Calculated MW:
60 kDa
Recommended Dilution:
IHC 1:100-500; WB 1:2000-10000; IF 1:200-1000; ELISA 1:5000-20000
UniProt:
Q9Y4K3
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.