The Recombinant WWOX Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C111312) against WWOX. Acts as a tumor suppressor and plays a role in apoptosis. May function synergistically with p53/TP53 to control genotoxic stress-induced cell death. Plays a role in TGFB1 signaling and TGFB1-mediated cell death. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF and FCM applications. It has been validated by WB analysis of MCF-7, Mouse ovary, Rat brain, IHC analysis of Human testis, Human cerebrum, Rat cerebrum, IF analysis of MCF7, MDA-MB-231(Negative cell line) and FCM analysis of MCF-7. The target is localized to the cytoplasm, nucleus.
Product Name:
Recombinant WWOX Monoclonal Antibody
SKU:
AGEL6617
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
5330426P09Rik, 9030416C10Rik, Aberrant WW domain-containing oxidoreductase, D16S432E, EC 1.1.1.-, EIEE, EIEE28, FOR, FRA16D, Fragile site FRA16D oxidoreductase, Fragile site FRA16D Oxireductase, HHCMA, HHCMA56, member 1, MGC55975, PRO, PRO0128, Putative oxidoreductase, SCAR, SCAR12, SDR41C, SDR41C1, Short chain dehydrogenase/reductase family 41C, WOX, WOX1, WW domain containing oxidoreductase, WW domain-containing oxidoreductase, WW domain-containing protein WWOX, WWOX, zgc:55975
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant human WWOX fragment
Applications:
WBIHCIFFCM
Clonality:
Recombinant Monoclonal
Clone No:
C111312
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
WWOX
Conjugation:
Unconjugated
Observed MW:
47 kDa
Calculated MW:
47 kDa
Recommended Dilution:
WB 1:500-2000; IHC 1:50-100; IF 1:200-500; FCM 1:50
UniProt:
Q9NZC7
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.