The Recombinant xCT Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110999) against xCT. This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF, IP and ELISA applications. It has been validated by WB analysis of unboiled HEK293. The target is localized to the membrane.
Product Name:
Recombinant xCT Monoclonal Antibody
SKU:
AGEL6305
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
Amino acid transport system xc xCT, Amino acid transport system xc-, Calcium channel blocker resistance protein CCBR1, CCBR, CCBR1, Cysteine/glutamate transporter, Cystine/glutamate transporter, member 11, OTTHUMP00000164578, SLC7A, SLC7A11, solute carrier family 7, Solute carrier family 7 member 11, SYSTEM Xc(-) TRANSPORTER-RELATED PROTEIN, xCT
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant Human xCT protein
Applications:
WBIHCIFIPELISA
Clonality:
Recombinant Monoclonal
Clone No:
C110999
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
xCT
Conjugation:
Unconjugated
Observed MW:
55 kDa
Calculated MW:
37 kDa
Recommended Dilution:
IHC 1:200-1000; WB 1:1000-5000; IF 1:200-1000; ELISA 1:5000-20000; IP 1:50-200
UniProt:
Q9UPY5
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
Western Blot with Recombinant xCT Monoclonal Antibody at dilution of 1:1000 dilution. Lane A: unboiled HEK293 whole cell lysate. Observed-MW:55 kDa Calculated-MW:37 kDa