RNF126 Rabbit Polyclonal Antibody (CAB20015)

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SKU:
CAB20015
€299

Description

Technical Manual

RNF126 Rabbit Polyclonal Antibody

Product Name:RNF126 Rabbit Polyclonal Antibody
Product SKU:CAB20015
Size:100 uL
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Background:

The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions.

Immunogen:Recombinant protein of human RNF126.
Sequence:

Email for sequence

Gene ID:55658
Swiss Prot:Q9BV68
Synonyms:RNF126
Calculated MW:33kDa/35kDa
Observed MW:33kDa
Reactivity:Human, Mouse, Rat
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Key:Western blotting Immunohistochemistry Immunofluorescence 
Positive Samples:HeLa, HepG2, K562, mouse testis, rat liver
Cellular Location:Cytoplasm, Nucleus

Product Images

RNF126 Rabbit Polyclonal Antibody (CAB20015)

Western blot - RNF126 Rabbit pAb (CAB20015)

Uniprot Information

UniProt Protein Function:RNF126: 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Ubiquitin conjugating system; EC 6.3.2.19; Ubiquitin ligase

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: cytoplasm; nucleus

Molecular Function:protein binding; zinc ion binding; epidermal growth factor receptor binding; ligase activity

Biological Process: protein monoubiquitination; negative regulation of epidermal growth factor receptor signaling pathway; proteasomal ubiquitin-dependent protein catabolic process; ubiquitin-dependent protein catabolic process via the multivesicular body pathway; protein ubiquitination during ubiquitin-dependent protein catabolic process; retrograde transport, endosome to Golgi; regulation of cell proliferation

NCBI Summary:The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. [provided by RefSeq, Jul 2008]
UniProt Code:Q9BV68
NCBI GenInfo Identifier:74762712
NCBI Gene ID:55658
NCBI Accession:Q9BV68.1
UniProt Secondary Accession:Q9BV68,Q9NWX1,
UniProt Related Accession:Q9BV68
Molecular Weight:311
NCBI Full Name:E3 ubiquitin-protein ligase RNF126
NCBI Synonym Full Names:ring finger protein 126
NCBI Official Symbol:RNF126 
NCBI Protein Information:E3 ubiquitin-protein ligase RNF126
UniProt Protein Name:E3 ubiquitin-protein ligase RNF126
UniProt Synonym Protein Names:RING finger protein 126
Protein Family:E3 ubiquitin-protein ligase
UniProt Gene Name:RNF126 
UniProt Entry Name:RN126_HUMAN
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Additional Information

Product type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
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