The RRM2 Monoclonal Antibody (CAB3424) is a high-quality antibody developed for reliable detection and analysis of target proteins. This gene encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. Transcription from this gene can initiate from alternative promoters, which results in two isoforms that differ in the lengths of their N-termini. Related pseudogenes have been identified on chromosomes 1 and X. RRID AB_2863055 Gene ID 6241 Swiss Prot Synonym R2; RR2; RR2M; C2orf48; RRM2
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
RRM2 Monoclonal Antibody
SKU:
CAB3424
Size:
100μL, 20μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC0775
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Tested Applications:
WBELISA
Recommended Dilution:
WB
1:500 - 1:1000
ELISA
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
R2, RR2, RR2M, C2orf48, RRM2
Positive Sample:
HeLa, A-375, Mouse liver, Rat liver
Cellular Localization:
Cytoplasm.
Calculated MW:
45kDa
Observed MW:
45kDa
This gene encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. Transcription from this gene can initiate from alternative promoters, which results in two isoforms that differ in the lengths of their N-termini. Related pseudogenes have been identified on chromosomes 1 and X. RRID AB_2863055 Gene ID 6241 Swiss Prot Synonym R2; RR2; RR2M; C2orf48; RRM2
Purification Method:
Affinity purification
Gene ID:
6241
RRID:
AB_2863055
Buffer Information:
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using RAbGn2 Rabbit mAb (CAB3424) at 1：1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
