Description
SARS-CoV-2 S - Trimer (WT) Recombinant Protein (C-His)
SARS-CoV-2 S - Trimer (WT) Recombinant Protein (C-His) is a recombinant protein expressed in mammalian cells, spanning Gln14-Gln1208, with a C-terminal His tag. Predicted molecular weight: 139.50 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Spike glycoprotein (Spike Protein (Trimer)) is a ~141 kDa protein. Attaches the virion to the cell membrane by interacting with host receptor, initiating the infection. For research use only.
The major receptor is host ACE2. When S2/S2' has been cleaved, binding to the receptor triggers direct fusion at the cell membrane. When S2/S2' has not been cleaved, binding to the receptor results in internalization of the virus by endocytosis using host TFRC and GRM2 and leading to fusion of the virion membrane with the host endosomal membrane. Alternatively, may use NRP1/NRP2 and integrin as entry receptors.
| Product Name: | SARS-CoV-2 S - Trimer (WT) Recombinant Protein (C-His) |
| SKU: | GXRP08378 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | SARS-CoV-2 |
| Synonyms: | E2, Peplomer protein, S, S glycoprotein, Spike glycoprotein, Spike protein S1, Spike protein S2, Spike protein S2' |
| Tag: | C-His |
| Expression Host: | Mammalian cells |
| Protein Length: | Gln14-Gln1208 |
| Calculated MW: | 139.50 kDa |
| UniProt: | P0DTC2 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
