The SIRT6 Antibody (CAB7416) is a high-quality antibody developed for reliable detection and analysis of target proteins. SIRT6, a member of the sirtuin family of proteins, is known for its role in DNA repair, genomic stability, and regulation of glucose and lipid metabolism.This antibody, produced in rabbits, is highly specific and sensitive for detecting SIRT6 in human samples. It has been validated for use in Western blotting applications, enabling researchers to visualize and quantify SIRT6 protein expression in different cell types and tissues.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
SIRT6 Antibody
SKU:
CAB7416
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Enables several functions, including NAD(P)+-protein-arginine ADP-ribosyltransferase activity; NAD-dependent histone deacetylase activity (H3-K9 specific); and transcription corepressor activity. Involved in several processes, including cellular protein modification process; negative regulation of nucleobase-containing compound metabolic process; and positive regulation of cell population proliferation. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; gonad; musculature; and retina. Used to study progeria. Orthologous to human SIRT6 (sirtuin 6).
Purification Method
Affinity purification
Gene ID
50721
RRID
AB_2767945
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using SIRT6 Rabbit pAb (CAB7416) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
