Anti-SLC39A6 Antibody (CAB4584)
- SKU:
- CAB4584
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- SLC39A6
- LIV-1
- ZIP6
Frequently bought together:
Description
| Product Name: | SLC39A6 Rabbit pAb |
| Product Code: | CAB4584 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | SLC39A6, LIV-1, ZIP6 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 170-320 of human SLC39A6 (NP_001092876.1). |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | MCF7, BT-474, A-549, HeLa, Rat testis |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 170-320 of human SLC39A6 (NP_001092876.1). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | KQFK DKKK KNQK KPEN DDDV EIKK QLSK YESQ LSTN EEKV DTDD RTEG YLRA DSQE PSHF DSQQ PAVL EEEE VMIA HAHP QEVY NEYV PRGC KNKC HSHF HDTL GQSD DLIH HHHD YHHI LHHH HHQN HHPH SHSQ RYSR EELK DAGV ATL |
| Gene ID: | 25800 |
| Uniprot: | Q13433 |
| Cellular Location: | Cell membrane, Multi-pass membrane protein |
| Calculated MW: | 48kDa/85kDa |
| Observed MW: | 102kDa |
| UniProt Protein Function: | SLC39A6: May act as a zinc-influx transporter. Belongs to the ZIP transporter (TC 2.A.5) family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Transporter, SLC family; Membrane protein, multi-pass; Membrane protein, integral; Transporter Chromosomal Location of Human Ortholog: 18q12.2 Cellular Component: cell surface; integral to plasma membrane; endoplasmic reticulum; plasma membrane Molecular Function:zinc ion transmembrane transporter activity Biological Process: cellular zinc ion homeostasis; transmembrane transport |
| NCBI Summary: | Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A6 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q13433 |
| NCBI GenInfo Identifier: | 292495066 |
| NCBI Gene ID: | 25800 |
| NCBI Accession: | Q13433.3 |
| UniProt Related Accession: | Q13433 |
| Molecular Weight: | |
| NCBI Full Name: | Zinc transporter ZIP6 |
| NCBI Synonym Full Names: | solute carrier family 39 member 6 |
| NCBI Official Symbol: | SLC39A6Â Â |
| NCBI Official Synonym Symbols: | ZIP6; LIV-1Â Â |
| NCBI Protein Information: | zinc transporter ZIP6 |
| UniProt Protein Name: | Zinc transporter ZIP6 |
| UniProt Synonym Protein Names: | Estrogen-regulated protein LIV-1; Solute carrier family 39 member 6; Zrt- and Irt-like protein 6; ZIP-6 |
| UniProt Gene Name: | SLC39A6Â Â |
| UniProt Entry Name: | S39A6_HUMAN |
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