The SMARCAD1 Antibody (CAB5850) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the SMARCA1 protein, this antibody allows for the detection and analysis of SMARCA1 in various cell types, making it an excellent choice for studies in epigenetics and cancer research.SMARCA1, also known as SNF2L, is a key player in chromatin remodeling processes that regulate gene expression. Dysregulation of SMARCA1 has been implicated in various diseases, including cancer, where it can impact cell proliferation, differentiation, and metastasis.
This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
SMARCAD1 Antibody
SKU:
CAB5850
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
HRZ, TYS, ETL1, HEL1, ADERM, BASNS, SMARCAD1
Cellular Localization:
Chromosome, Nucleus.
Calculated MW:
117kDa
Observed MW:
Refertofigures
This gene encodes a member of the SNF subfamily of helicase proteins. The encoded protein plays a critical role in the restoration of heterochromatin organization and propagation of epigenetic patterns following DNA replication by mediating histone H3/H4 deacetylation. Mutations in this gene are associated with adermatoglyphia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method
Affinity purification
Gene ID
56916
RRID
AB_2766600
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Immunofluorescence analysis of A549 cells using SMARCAD1 Rabbit pAb (CAB5850). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
