The SPTBN1 Antibody (CAB5253) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it suitable for a variety of research applications.SPTBN1 is a key cytoskeletal protein involved in maintaining cell shape and structure, as well as playing a role in cell adhesion and migration. Dysregulation of SPTBN1 has been linked to various diseases, including cancer and neurological disorders. The CAB5253 antibody binds specifically to the SPTBN1 protein, enabling researchers to detect and analyze its expression in different cell types.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
SPTBN1 Antibody
SKU:
CAB5253
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:
PPSP EPST KVSE EAES QQQW DTSK GEQV SQNG LPAE QGSP RMAE TVDT SEMV NGAT EQRT SSKE SSPI PSPT SDRK AKTA LPAQ SAAT LPAR TQET PSAQ M
Tested Applications:
WBELISA
Recommended Dilution:
WB
1:1000 - 1:3000
ELISA
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein contains an N-terminal actin-binding domain, and 17 spectrin repeats which are involved in dimer formation. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method
Affinity purification
Gene ID
6711
RRID
AB_2766081
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SPTBN1 Rabbit pAb (CAB5253) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
