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Anti-SRP54 Antibody (CAB2296)

SKU:
CAB2296
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
€139 - €419
Frequently bought together:

Description

Product Name:SRP54 Rabbit mAb
Product Code:CAB2296
Size:20uL, 50uL, 100uL
Applications:WB, IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human SRP54
Applications:WB, IF
Recommended Dilutions:WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:HeLa, Jurkat
Immunogen:A synthesized peptide derived from human SRP54
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:6729
Uniprot:P61011
Calculated MW:54kDa
Observed MW:54KDa
UniProt Protein Function:SRP54: Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:RNA-binding

Chromosomal Location of Human Ortholog: 14q13.2

Cellular Component: cytoplasm; signal recognition particle, endoplasmic reticulum targeting; nucleolus; nuclear speck; nucleus; cytosol

Molecular Function:GTPase activity; ribonucleoprotein binding; GDP binding; GTP binding; drug binding; endoplasmic reticulum signal peptide binding; 7S RNA binding

Biological Process: response to drug; SRP-dependent cotranslational protein targeting to membrane, translocation; SRP-dependent cotranslational protein targeting to membrane; protein targeting to ER; cellular protein metabolic process; translation; SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition; gene expression

UniProt Code:P61011
NCBI GenInfo Identifier:46577650
NCBI Gene ID:6729
NCBI Accession:P61011.1
UniProt Secondary Accession:P61011,P14576,
UniProt Related Accession:P61011
Molecular Weight:504
NCBI Full Name:Signal recognition particle 54 kDa protein
NCBI Synonym Full Names:signal recognition particle 54kDa
NCBI Official Symbol:SRP54  
NCBI Protein Information:signal recognition particle 54 kDa protein; signal recognition particle 54kD
UniProt Protein Name:Signal recognition particle 54 kDa protein
Protein Family:Signal recognition particle
UniProt Gene Name:SRP54  
UniProt Entry Name:SRP54_HUMAN

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