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Anti-SUPT20H Antibody (CAB7374)

SKU:
CAB7374
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Autophagy
  • Autophagy Antibodies Anti-SUPT20H Antibody CAB7374
  • Autophagy Antibodies Anti-SUPT20H Antibody CAB7374
  • Autophagy Antibodies Anti-SUPT20H Antibody CAB7374
  • Autophagy Antibodies Anti-SUPT20H Antibody CAB7374
  • Autophagy Antibodies Anti-SUPT20H Antibody CAB7374
€139 - €419
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Description

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Antibody Name:Anti-SUPT20H Antibody
Antibody SKU:CAB7374
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 580-779 of human SUPT20H (NP_001014308.2).
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:SW480, HL-60, Mouse testis, Mouse brain, Mouse lung, Rat kidney, Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 580-779 of human SUPT20H (NP_001014308.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:NLSG LLPS GGLL PNAL PSAM QAAS QAGV PFGL KNTS SLRP LNLL QLPG GSLI FNTL QQQQ QQLS QFTP QQPQ QPTT CSPQ QPGE QGSE QGST SQEQ ALSA QQAA VINL TGVG SFMQ SQAA VLSQ LGSA ENRP EQSL PQQR FQLS SAFQ QQQQ QIQQ LRFL QHQM AMAA AAAQ TAQL HHHR HTGS QSKS KMKR GTPT TPKF
Gene ID:55578
Uniprot:Q8NEM7
Cellular Location:Nucleus
Calculated MW:80kDa/85kDa/88kDa
Observed MW:86kDa
Synonyms:SUPT20H, C13, C13orf19, FAM48A, FP757, P38IP, SPT20
Background:
UniProt Protein Function:FAM48A: Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) activation during gastrulation. Required for down- regulation of E-cadherin during gastrulation by regulating E- cadherin protein level downstream from NCK-interacting kinase (NIK) and independently of the regulation of transcription by FGF signaling and Snail. Required for starvation- induced ATG9A trafficking during autophagy. Belongs to the FAM48 family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Unknown function

Chromosomal Location of Human Ortholog: 13q13.3

Cellular Component: nucleolus

Molecular Function:protein binding; transcription cofactor activity

Biological Process: establishment and/or maintenance of chromatin architecture; autophagy; gastrulation

UniProt Code:Q8NEM7
NCBI GenInfo Identifier:334302791
NCBI Gene ID:55578
NCBI Accession:Q8NEM7.2
UniProt Secondary Accession:Q8NEM7,Q71RF3, Q9Y6A6, E7ER46,
UniProt Related Accession:Q8NEM7
Molecular Weight:779
NCBI Full Name:Transcription factor SPT20 homolog
NCBI Synonym Full Names:suppressor of Ty 20 homolog (S. cerevisiae)
NCBI Official Symbol:SUPT20H  
NCBI Official Synonym Symbols:C13; FP757; P38IP; SPT20; FAM48A; C13orf19  
NCBI Protein Information:transcription factor SPT20 homolog; protein FAM48A; tumor rejection antigen; family with sequence similarity 48, member A; transcription factor (p38 interacting protein)
UniProt Protein Name:Transcription factor SPT20 homolog
UniProt Synonym Protein Names:p38-interacting protein; p38IP
Protein Family:Transcription factor
UniProt Gene Name:SUPT20H  
UniProt Entry Name:SP20H_HUMAN
Anti-SUPT20H Antibody (CAB7374)Western blot analysis of extracts of various cell lines, using SUPT20H antibody (CAB7374) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.
Anti-SUPT20H Antibody (CAB7374)Immunohistochemistry of paraffin-embedded human colon using SUPT20H antibody (CAB7374) at dilution of 1:100 (40x lens).
Anti-SUPT20H Antibody (CAB7374)Immunohistochemistry of paraffin-embedded human kidney using SUPT20H antibody (CAB7374) at dilution of 1:100 (40x lens).
Anti-SUPT20H Antibody (CAB7374)Immunohistochemistry of paraffin-embedded mouse liver using SUPT20H antibody (CAB7374) at dilution of 1:100 (40x lens).
Anti-SUPT20H Antibody (CAB7374)Immunofluorescence analysis of A549 cells using SUPT20H antibody (CAB7374). Blue: DAPI for nuclear staining.

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