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Anti-TENM1 Antibody (CAB15774)

SKU:
CAB15774
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Metabolism
  • Metabolism Antibodies 3 Anti-TENM1 Antibody CAB15774
  • Metabolism Antibodies 3 Anti-TENM1 Antibody CAB15774
  • Metabolism Antibodies 3 Anti-TENM1 Antibody CAB15774
  • Metabolism Antibodies 3 Anti-TENM1 Antibody CAB15774
€139 - €419
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Description

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Antibody Name:Anti-TENM1 Antibody
Antibody SKU:CAB15774
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 350-540 of human TENM1 (NP_001156750.1).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:U-87MG, U-251MG, HeLa
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 350-540 of human TENM1 (NP_001156750.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:QPVE GELY ANGV SKGN RGTE SMDT TYSP IGGK VSDK SEKK VFQK GRAI DTGE VDIG AQVM QTIP PGLF WRFQ ITIH HPIY LKFN ISLA KDSL LGIY GRRN IPPT HTQF DFVK LMDG KQLV KQDS KGSD DTQH SPRN LILT SLQE TGFI EYMD QGPW YLAF YNDG KKME QVFV LTTA IEIM DDCS TNCN GNG
Gene ID:10178
Uniprot:Q9UKZ4
Cellular Location:Cell membrane, Cytoplasm, Nucleus, Nucleus matrix, Nucleus speckle, Single-pass membrane protein, cytoskeleton
Calculated MW:305kDa
Observed MW:280kDa
Synonyms:TENM1, ODZ1, ODZ3, TEN-M1, TNM, TNM1
Background:The protein encoded by this gene belongs to the tenascin family and teneurin subfamily. It is expressed in the neurons and may function as a cellular signal transducer. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
UniProt Protein Function:ODZ1: May function as a cellular signal transducer. Belongs to the tenascin family. Teneurin subfamily. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Membrane protein, integral

Chromosomal Location of Human Ortholog: Xq25

Cellular Component: cytoplasm; cytoskeleton; endoplasmic reticulum; extracellular region; Golgi apparatus; integral to plasma membrane; nuclear matrix; nuclear speck; nucleus; perinuclear region of cytoplasm; plasma membrane

Molecular Function:heparin binding; protein heterodimerization activity; protein homodimerization activity

Biological Process: immune response; negative regulation of cell proliferation; nervous system development; neuropeptide signaling pathway; positive regulation of actin filament polymerization; positive regulation of filopodium formation; positive regulation of MAP kinase activity; positive regulation of peptidyl-serine phosphorylation; regulation of transcription from RNA polymerase III promoter; transcription, DNA-dependent

NCBI Summary:The protein encoded by this gene belongs to the tenascin family and teneurin subfamily. It is expressed in the neurons and may function as a cellular signal transducer. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
UniProt Code:Q9UKZ4
NCBI GenInfo Identifier:110347400
NCBI Gene ID:10178
NCBI Accession:NP_055068.2
UniProt Secondary Accession:Q9UKZ4,Q5JZ17, B2RTR5,
UniProt Related Accession:Q9UKZ4
Molecular Weight:305,947 Da
NCBI Full Name:teneurin-1 isoform 3
NCBI Synonym Full Names:teneurin transmembrane protein 1
NCBI Official Symbol:TENM1  
NCBI Official Synonym Symbols:TNM; ODZ1; ODZ3; TNM1; TEN-M1  
NCBI Protein Information:teneurin-1
UniProt Protein Name:Teneurin-1
UniProt Synonym Protein Names:Protein Odd Oz/ten-m homolog 1; Tenascin-M1; Ten-m1
UniProt Gene Name:TENM1  
UniProt Entry Name:TEN1_HUMAN
Anti-TENM1 Antibody (CAB15774)Western blot analysis of extracts of various cell lines, using TENM1 antibody (CAB15774) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
Anti-TENM1 Antibody (CAB15774)Immunofluorescence analysis of C6 cells using TENM1 antibody (CAB15774) at dilution of 1:100. Blue: DAPI for nuclear staining.
Anti-TENM1 Antibody (CAB15774)Immunofluorescence analysis of L929 cells using TENM1 antibody (CAB15774) at dilution of 1:100. Blue: DAPI for nuclear staining.
Anti-TENM1 Antibody (CAB15774)Immunofluorescence analysis of U-2 OS cells using TENM1 antibody (CAB15774) at dilution of 1:100. Blue: DAPI for nuclear staining.

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