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Anti-TIMM17B Antibody (CAB8477)

SKU:
CAB8477
Product Type:
Antibody
Applications:
WB
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
€139 - €419
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Description

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Antibody Name:Anti-TIMM17B Antibody
Antibody SKU:CAB8477
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-172 of human TIMM17B (NP_005825.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse
Positive Samples:Mouse heart
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-172 of human TIMM17B (NP_005825.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MEEY AREP CPWR IVDD CGGA FTMG VIGG GVFQ AIKG FRNA PVGI RHRL RGSA NAVR IRAP QIGG SFAV WGGL FSTI DCGL VRLR GKED PWNS ITSG ALTG AVLA ARSG PLAM VGSA MMGG ILLA LIEG VGIL LTRY TAQQ FRNA PPFL EDPS QLPP KDGT PAPG YPSY QQYH
Gene ID:10245
Uniprot:O60830
Cellular Location:Mitochondrion inner membrane, Multi-pass membrane protein
Calculated MW:18kDa/23kDa
Observed MW:18kDa
Synonyms:TIMM17B, DXS9822, JM3, TIM17B
Background:This gene encodes a multipass transmembrane protein that forms an integral component of the mitochondrial translocase TIM23 complex. This complex facilitates the transport of mitochondrial proteins from the cytosol across the mitochondrial inner membrane and into the mitochondrion. There is a pseudogene for this gene on chromosome 12. Alternative splicing results in multiple transcript variants.
UniProt Protein Function:Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
NCBI Summary:This gene encodes a multipass transmembrane protein that forms an integral component of the mitochondrial translocase TIM23 complex. This complex facilitates the transport of mitochondrial proteins from the cytosol across the mitochondrial inner membrane and into the mitochondrion. There is a pseudogene for this gene on chromosome 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
UniProt Code:O60830
NCBI GenInfo Identifier:269784613
NCBI Gene ID:10245
NCBI Accession:NP_001161419.1
UniProt Secondary Accession:O60830,Q9UJV0, A8K2E2, J3KPV3,
UniProt Related Accession:O60830
Molecular Weight:23,824 Da
NCBI Full Name:mitochondrial import inner membrane translocase subunit Tim17-B isoform 1
NCBI Synonym Full Names:translocase of inner mitochondrial membrane 17B
NCBI Official Symbol:TIMM17B  
NCBI Official Synonym Symbols:JM3; TIM17B; DXS9822  
NCBI Protein Information:mitochondrial import inner membrane translocase subunit Tim17-B
UniProt Protein Name:Mitochondrial import inner membrane translocase subunit Tim17-B
UniProt Gene Name:TIMM17B  
Anti-TIMM17B Polyclonal Antibody (CAB8477)Western blot analysis of extracts of mouse heart, using TIMM17B antibody (CAB8477) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.

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