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Anti-TIMM23 Antibody (CAB8688)

SKU:
CAB8688
Product Type:
Antibody
Applications:
WB
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
  • Cell Biology Antibodies 12 Anti-TIMM23 Antibody CAB8688
  • Cell Biology Antibodies 12 Anti-TIMM23 Antibody CAB8688
  • Cell Biology Antibodies 12 Anti-TIMM23 Antibody CAB8688
€139 - €419
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Description

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Antibody Name:Anti-TIMM23 Antibody
Antibody SKU:CAB8688
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-209 of human TIMM23 (NP_006318.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:SH-SY5Y, SW620, HepG2, MCF7, Mouse heart, Rat brain, Rat heart, Rat lung
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-209 of human TIMM23 (NP_006318.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MEGG GGSG NKTT GGLA GFFG AGGA GYSH ADLA GVPL TGMN PLSP YLNV DPRY LVQD TDEF ILPT GANK TRGR FELA FFTI GGCC MTGA AFGA MNGL RLGL KETQ NMAW SKPR NVQI LNMV TRQG ALWA NTLG SLAL LYSA FGVI IEKT RGAE DDLN TVAA GTMT GMLY KCTG GLRG IARG GLTG LTLT SLYA LYNN WEHM KGSL LQQS L
Gene ID:100287932
Uniprot:O14925
Cellular Location:Mitochondrion inner membrane, Multi-pass membrane protein
Calculated MW:21kDa
Observed MW:21kDa
Synonyms:TIMM23, TIM23
Background:The protein encoded by this gene is part of a complex located in the inner mitochondrial membrane that mediates the transport of transit peptide-containing proteins across the membrane. Multiple transcript variants, one protein-coding and others not protein-coding, have been found for this gene.
UniProt Protein Function:TIMM23: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Belongs to the Tim17/Tim22/Tim23 family.
UniProt Protein Details:

Protein type:Membrane protein, multi-pass; Membrane protein, integral; Mitochondrial

Chromosomal Location of Human Ortholog: 10q11.23

Cellular Component: integral to mitochondrial inner membrane; mitochondrial inner membrane; mitochondrial inner membrane presequence translocase complex; mitochondrial intermembrane space; mitochondrion

Molecular Function:protein binding; protein channel activity

Biological Process: protein import into mitochondrial matrix; protein targeting to mitochondrion

NCBI Summary:The protein encoded by this gene is part of a complex located in the inner mitochondrial membrane that mediates the transport of transit peptide-containing proteins across the membrane. Multiple transcript variants, one protein-coding and others not protein-coding, have been found for this gene. [provided by RefSeq, Jul 2012]
UniProt Code:O14925
NCBI GenInfo Identifier:18201964
NCBI Gene ID:100287932
NCBI Accession:O14925.1
UniProt Secondary Accession:O14925,Q53FF8, Q5T1E6, Q6P5S5,
UniProt Related Accession:O14925
Molecular Weight:21,943 Da
NCBI Full Name:Mitochondrial import inner membrane translocase subunit Tim23
NCBI Synonym Full Names:translocase of inner mitochondrial membrane 23
NCBI Official Symbol:TIMM23  
NCBI Official Synonym Symbols:TIM23  
NCBI Protein Information:mitochondrial import inner membrane translocase subunit Tim23
UniProt Protein Name:Mitochondrial import inner membrane translocase subunit Tim23
Protein Family:Mitochondrial import inner membrane translocase
UniProt Gene Name:TIMM23  
UniProt Entry Name:TIM23_HUMAN
Anti-TIMM23 Polyclonal Antibody (CAB8688)Western blot analysis of extracts of various cell lines, using TIMM23 antibody (CAB8688) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s.
Anti-TIMM23 Polyclonal Antibody (CAB8688)Western blot analysis of extracts of Mouse heart, using TIMM23 antibody (CAB8688) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 30s.
Anti-TIMM23 Polyclonal Antibody (CAB8688)Western blot analysis of extracts of various cell lines, using TIMM23 antibody (CAB8688) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.

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