DR5/TRAILR2/TNFRSF10B Rabbit Polyclonal Antibody (CAB1236)
- SKU:
- CAB1236
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | DR5/TRAILR2/TNFRSF10B Rabbit Polyclonal Antibody |
SKU: | CAB1236 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 260-440 of human DR5/TRAILR2/TNFRSF10B (NP_003833.4). |
Sequence: | RSSQ RPGA EDNV LNEI VSIL QPTQ VPEQ EMEV QEPA EPTG VNML SPGE SEHL LEPA EAER SQRR RLLV PANE GDPT ETLR QCFD DFAD LVPF DSWE PLMR KLGL MDNE IKVA KAEA AGHR DTLY TMLI KWVN KTGR DASV HTLL DALE TLGE RLAK QKIE DHLL SSGK FMYL EGNA DSAM S |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | DR5; CD262; KILLER; TRICK2; TRICKB; ZTNFR9; TRAILR2; TRICK2A; TRICK2B; TRAIL-R2; KILLER/DR5; DR5/TRAILR2/TNFRSF10B |
Positive Sample: | Jurkat |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 48kDa |
Observed MW: | 48kDa |
The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 8795 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |