null

Anti-TOMM40 Antibody (CAB3213)

SKU:
CAB3213
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Signal Transduction
  • Signal Transduction Antibodies 2 Anti-TOMM40 Antibody CAB3213
  • Signal Transduction Antibodies 2 Anti-TOMM40 Antibody CAB3213
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-TOMM40 Antibody
Antibody SKU:CAB3213
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human TOMM40 (NP_001122389.1).
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:U-2OS, HepG2, Mouse brain, Mouse testis, Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human TOMM40 (NP_001122389.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MGNV LAAS SPPA GPPP PPAP ALVG LPPP PPSP PGFT LPPL GGSL GAGT STSR SSER TPGA ATAS ASGA AEDG ACGC LPNP GTFE ECHR KC
Gene ID:10452
Uniprot:O96008
Cellular Location:Mitochondrion outer membrane, Multi-pass membrane protein
Calculated MW:34kDa/37kDa
Observed MW:38kDa
Synonyms:TOMM40, C19orf1, D19S1177E, PER-EC1, PEREC1, TOM40
Background:The protein encoded by this gene is localized in the outer membrane of the mitochondria. It is the channel-forming subunit of the translocase of the mitochondrial outer membrane (TOM) complex that is essential for import of protein precursors into mitochondria. Alternatively spliced transcript variants have been found for this gene.
UniProt Protein Function:TOMM40: Channel-forming protein essential for import of protein precursors into mitochondria. Belongs to the Tom40 family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Membrane protein, multi-pass; Mitochondrial

Chromosomal Location of Human Ortholog: 19q13

Cellular Component: nucleoplasm; pore complex; mitochondrial outer membrane translocase complex; mitochondrion; cytoplasm; integral to membrane; integral to mitochondrial outer membrane

Molecular Function:protein transmembrane transporter activity; porin activity

Biological Process: cellular protein metabolic process; ion transport; protein targeting to mitochondrion

NCBI Summary:The protein encoded by this gene is localized in the outer membrane of the mitochondria. It is the channel-forming subunit of the translocase of the mitochondrial outer membrane (TOM) complex that is essential for import of protein precursors into mitochondria. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2015]
UniProt Code:O96008
NCBI GenInfo Identifier:12230369
NCBI Gene ID:10452
NCBI Accession:O96008.1
UniProt Related Accession:O96008
Molecular Weight:Observed MW: 38kDa
NCBI Full Name:Mitochondrial import receptor subunit TOM40 homolog
NCBI Synonym Full Names:translocase of outer mitochondrial membrane 40
NCBI Official Symbol:TOMM40  
NCBI Official Synonym Symbols:TOM40; PEREC1; C19orf1; PER-EC1; D19S1177E  
NCBI Protein Information:mitochondrial import receptor subunit TOM40 homolog
UniProt Protein Name:Mitochondrial import receptor subunit TOM40 homolog
UniProt Synonym Protein Names:Protein Haymaker; Translocase of outer membrane 40 kDa subunit homolog; p38.5
Protein Family:Mitochondrial import receptor
UniProt Gene Name:TOMM40  
UniProt Entry Name:TOM40_HUMAN
Anti-TOMM40 Antibody (CAB3213)Western blot analysis of extracts of various cell lines, using TOMM40 antibody (CAB3213) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s.
Anti-TOMM40 Antibody (CAB3213)Confocal immunofluorescence analysis of U2OS cells using TOMM40 Polyclonal Antibody (CAB3213) at dilution of 1:200. Blue: DAPI for nuclear staining.

Related Products