Torapsel (Research-Grade) is a research-grade biosimilar antibody targeting CD62P. Reactivity: Human. Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% purity as determined by SDS-PAGE. For research use only.
P-selectin (CD62P/SELP) is a ~90 kDa protein. Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with SELPLG. Mediates cell-cell interactions and cell adhesion via the interaction with integrin alpha-IIb/beta3 (ITGA2B:ITGB3) and integrin alpha-V/beta-3 (ITGAV:ITGB3).
Product Name:
Torapsel (Research-Grade)
SKU:
GXBS01468
Size:
100 µg, 1 mg
Target:
Leukocyte-endothelial cell adhesion molecule 3
Isotype:
Fusion - [SELPLG (selectin P ligand, selectin P glycoprotein ligand, PSGL-1, CD162) 42-89]2 - IGHG1 Fc (Fragment constant)
Host Species:
Human
Reactivity:
Human
Applications:
ELISA, Functional assay, Research in vivo
Expression Host:
Mammalian cells
Synonyms:
42-89-glycoprotein, WAY164339, pMT21:PL85
Purity:
>95% purity as determined by SDS-PAGE.
Endotoxin Level:
< 10 EU/mg
Formulation:
0.01M PBS pH 7.4
State of Matter:
Liquid
Regulatory Status:
For research use only. Not suitable for clinical or therapeutic use.
Product Preparation:
Protein A/G purified from cell culture supernatant.
Storage and Handling:
Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
