UniProt Protein Function: | TREML2: Cell surface receptor that may play a role in the innate and adaptive immune response. Acts as a counter-receptor for CD276 and interaction with CD276 on T-cells enhances T-cell activation.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 6p21.1Cellular Component: cell surface; integral to membrane; plasma membraneMolecular Function: protein binding; receptor activityBiological Process: T cell activation |
UniProt Protein Details: | |
NCBI Summary: | TREML2 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1 (MIM 605085) and TREM2 (MIM 605086), but it has distinct structural and functional properties (Allcock et al., 2003 [PubMed 12645956]).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q5T2D2 |
NCBI GenInfo Identifier: | 170932501 |
NCBI Gene ID: | 79865 |
NCBI Accession: | NP_079083.2 |
UniProt Secondary Accession: | Q5T2D2 |
UniProt Related Accession: | Q5T2D2 |
Molecular Weight: | |
NCBI Full Name: | trem-like transcript 2 protein |
NCBI Synonym Full Names: | triggering receptor expressed on myeloid cells like 2 |
NCBI Official Symbol: | TREML2Â Â |
NCBI Official Synonym Symbols: | TLT2; TLT-2; C6orf76; dJ238O23.1Â Â |
NCBI Protein Information: | trem-like transcript 2 protein |
UniProt Protein Name: | Trem-like transcript 2 protein |
UniProt Synonym Protein Names: | Triggering receptor expressed on myeloid cells-like protein 2 |
Protein Family: | |
UniProt Gene Name: | TREML2Â Â |
UniProt Entry Name: | TRML2_HUMAN |