null

TRIM24 Rabbit Polyclonal Antibody (CAB10546)

SKU:
CAB10546
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:TRIM24 Rabbit Polyclonal Antibody
SKU:CAB10546
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 600-820 of human TRIM24 (NP_056989.2).
Sequence:DGKA FGSP MIDL SSPV GGSY NLPS LPDI DCSS TIML DNIV RKDT NIDH GQPR PPSN RTVQ SPNS SVPS PGLA GPVT MTSV HPPI RSPS ASSV GSRG SSGS SSKP AGAD STHK VPVV MLEP IRIK QENS GPPE NYDF PVVI VKQE SDEE SRPQ NANY PRSI LTSL LLNS SQSS TSEE TVLR SDAP DSTG DQPG LHQD NSSN GKSE WLDP SQKS PLHV GETR K
Tested Applications:WB ELISA
Recommended Dilution:WB,1:1000 - 1:2000
Synonyms:PTC6; TF1A; TIF1; RNF82; TIF1A; hTIF1; TIF1ALPHA; TRIM24
Positive Sample:293T,HeLa
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Nucleus.
Calculated MW:117kDa
Observed MW:117kDa

The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Purification Method:Affinity purification
Gene ID:8805
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using TRIM24 Rabbit pAb (CAB10546) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.

Related Products