Anti-TRIM29 Antibody (CAB7508)

Antibody Name:	Anti-TRIM29 Antibody
Antibody SKU:	CAB7508
Antibody Size:	20uL, 50uL, 100uL
Application:	WB IHC
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 309-588 of human TRIM29 (NP_036233.2).

Application:	WB IHC
Recommended Dilution:	WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:	Human, Mouse, Rat
Positive Samples:	Mouse thymus

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 309-588 of human TRIM29 (NP_036233.2).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	ILEQ NFRD LVRD LEKQ KEEV RAAL EQRE QDAV DQVK VIMD ALDE RAKV LHED KQTR EQLH SISD SVLF LQEF GALM SNYS LPPP LPTY HVLL EGEG LGQS LGNF KDDL LNVC MRHV EKMC KADL SRNF IERN HMEN GGDH RYVN NYTN SFGG EWSA PDTM KRYS MYLT PKGG VRTS YQPS SPGR FTKE TTQK NFNN LYGT KGNY TSRV WEYS SSIQ NSDN DLPV VQGS SSFS LKGY PSLM RSQS PKAQ PQTW KSGK QTML SHYR PFYV NKGN GIGS NEAP
Gene ID:	23650
Uniprot:	Q14134
Cellular Location:	Cytoplasm
Calculated MW:	63kDa/65kDa
Observed MW:	68kDa

Synonyms:

TRIM29, ATDC

Background:

The protein encoded by this gene belongs to the TRIM protein family. It has multiple zinc finger motifs and a leucine zipper motif. It has been proposed to form homo- or heterodimers which are involved in nucleic acid binding. Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. It may also function in the suppression of radiosensitivity since it is associated with ataxia telangiectasia phenotype.

UniProt Protein Function:	TRIM29: It is able to complement the radiosensitivity defect of an ataxia telangiectasia (AT) fibroblast cell line. Interacts with VIM and HINT1. Expressed in placenta, prostate and thymus. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:	Protein type:Transcription factor Chromosomal Location of Human Ortholog: 11q23.3 Cellular Component: nucleoplasm; intermediate filament cytoskeleton; cytoplasm Molecular Function:protein binding; zinc ion binding; p53 binding; transcription factor activity Biological Process: transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter
NCBI Summary:	The protein encoded by this gene belongs to the TRIM protein family. It has multiple zinc finger motifs and a leucine zipper motif. It has been proposed to form homo- or heterodimers which are involved in nucleic acid binding. Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. It may also function in the suppression of radiosensitivity since it is associated with ataxia telangiectasia phenotype. [provided by RefSeq, Jul 2008]
UniProt Code:	Q14134
NCBI GenInfo Identifier:	116242825
NCBI Gene ID:	23650
NCBI Accession:	Q14134.2
UniProt Secondary Accession:	Q14134,Q8R2Q0,
UniProt Related Accession:	Q14134
Molecular Weight:	588
NCBI Full Name:	Tripartite motif-containing protein 29
NCBI Synonym Full Names:	tripartite motif containing 29
NCBI Official Symbol:	TRIM29
NCBI Official Synonym Symbols:	ATDC
NCBI Protein Information:	tripartite motif-containing protein 29; tripartite motif-containing 29; tripartite motif protein TRIM29; ataxia telangiectasia group D-associated protein; ataxia-telangiectasia group D-associated protein
UniProt Protein Name:	Tripartite motif-containing protein 29
UniProt Synonym Protein Names:	Ataxia telangiectasia group D-associated protein
Protein Family:	Tripartite motif-containing protein
UniProt Gene Name:	TRIM29
UniProt Entry Name:	TRI29_HUMAN

	Western blot analysis of extracts of mouse thymus, using TRIM29 antibody (CAB7508) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
	Immunohistochemistry of paraffin-embedded rat brain using TRIM29 Antibody (CAB7508) at dilution of 1:100 (40x lens).

Antibodies

Anti-TRIM29 Antibody (CAB4576)

TRIM29 Antibody (PACO12912)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)