Trosovavilp alfa (Research-Grade) is a research-grade biosimilar antibody targeting virus-like-particle (VLP). Format: virus-like-particle (VLP). Reactivity: Chikungunya virus (CHIKV). Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, flow cytometry and functional assays. Endotoxin: < 10 EU/mg. Purity: >95% as determined by SDS-PAGE. For research use only.
Structural polyprotein is a ~138 kDa protein. Forms an icosahedral capsid with a T=4 symmetry composed of 240 copies of the capsid protein surrounded by a lipid membrane through which penetrate 80 spikes composed of trimers of E1-E2 heterodimers. The capsid protein binds to the viral RNA genome at a site adjacent to a ribosome binding site for viral genome translation following genome release. Possesses a protease activity that results in its autocatalytic cleavage from the nascent structural protein. Following its self-cleavage, the capsid protein transiently associates with ribosomes, and within several minutes the protein binds to viral RNA and rapidly assembles into icosahedric core particles. The resulting nucleocapsid eventually associates with the cytoplasmic domain of the spike glycoprotein E2 at the cell membrane, leading to budding and formation of mature virions.
Product Name:
Trosovavilp alfa (Research-Grade)
SKU:
GXBS02694
Size:
100 µg, 1 mg
Target:
virus-like-particle (VLP)
Isotype:
virus-like-particle (VLP)
Reactivity:
Chikungunya virus (CHIKV)
Applications:
ELISA, FACS, Functional assay
Synonyms:
CAS: 2986379-37-5
Purity:
>95% as determined by SDS-PAGE
Endotoxin Level:
< 10 EU/mg
Formulation:
0.01M PBS pH 7.4
Regulatory Status:
For research use only.
Storage and Handling:
Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
