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Anti-TUBB8 Antibody (CAB12617)

SKU:
CAB12617
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
  • Cell Biology Antibodies 3 Anti-TUBB8 Antibody CAB12617
  • Cell Biology Antibodies 3 Anti-TUBB8 Antibody CAB12617
  • Cell Biology Antibodies 3 Anti-TUBB8 Antibody CAB12617
  • Cell Biology Antibodies 3 Anti-TUBB8 Antibody CAB12617
€139 - €419
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Description

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Antibody Name:Anti-TUBB8 Antibody
Antibody SKU:CAB12617
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthetic peptide of human TUBB8
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:LO2, Jurkat, HepG2, A-549, Mouse liver, Rat brain
Immunogen:A synthetic peptide of human TUBB8
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:347688
Uniprot:Q3ZCM7
Cellular Location:Cytoplasm, cytoskeleton
Calculated MW:49kDa
Observed MW:54kDa
Synonyms:TUBB8, OOMD, OOMD2, bA631M21.2
Background:The protein encoded by this gene represents the primary beta-tubulin subunit of oocytes and the early embryo. Defects in this gene, which is primate-specific, are a cause of oocyte maturation defect 2 and infertility.
UniProt Protein Function:TUBB8: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. Belongs to the tubulin family.
UniProt Protein Details:

Protein type:Cytoskeletal

Chromosomal Location of Human Ortholog: 10p15.3

NCBI Summary:The protein encoded by this gene represents the primary beta-tubulin subunit of oocytes and the early embryo. Defects in this gene, which is primate-specific, are a cause of oocyte maturation defect 2 and infertility. [provided by RefSeq, Mar 2016]
UniProt Code:Q3ZCM7
NCBI GenInfo Identifier:182705285
NCBI Gene ID:347688
NCBI Accession:Q3ZCM7.2
UniProt Secondary Accession:Q3ZCM7,Q5SQX9, Q8WZ78,
UniProt Related Accession:Q3ZCM7
Molecular Weight:49,776 Da
NCBI Full Name:Tubulin beta-8 chain
NCBI Synonym Full Names:tubulin beta 8 class VIII
NCBI Official Symbol:TUBB8  
NCBI Official Synonym Symbols:OOMD; OOMD2; bA631M21.2  
NCBI Protein Information:tubulin beta-8 chain
UniProt Protein Name:Tubulin beta-8 chain
Protein Family:Tubulin
UniProt Gene Name:TUBB8  
UniProt Entry Name:TBB8_HUMAN
Anti-TUBB8 Antibody (CAB12617)Western blot analysis of extracts of various cell lines, using TUBB8 antibody (CAB12617) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
Anti-TUBB8 Antibody (CAB12617)Immunohistochemistry of paraffin-embedded human stomach using TUBB8 antibody (CAB12617) at dilution of 1:100 (40x lens).
Anti-TUBB8 Antibody (CAB12617)Immunohistochemistry of paraffin-embedded rat kidney using TUBB8 antibody (CAB12617) at dilution of 1:100 (40x lens).
Anti-TUBB8 Antibody (CAB12617)Immunofluorescence analysis of U2OS cells using TUBB8 antibody (CAB12617) at dilution of 1:100. Blue: DAPI for nuclear staining.

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