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Anti-UQCR10 Antibody (CAB12587)

SKU:
CAB12587
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
  • Cell Biology Antibodies 3 Anti-UQCR10 Antibody CAB12587
  • Cell Biology Antibodies 3 Anti-UQCR10 Antibody CAB12587
  • Cell Biology Antibodies 3 Anti-UQCR10 Antibody CAB12587
  • Cell Biology Antibodies 3 Anti-UQCR10 Antibody CAB12587
€139 - €419
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Description

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Antibody Name:Anti-UQCR10 Antibody
Antibody SKU:CAB12587
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-63 of human UQCR10 (NP_037519.2).
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:22Rv1, NCI-H460, Mouse kidney, Rat heart
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-63 of human UQCR10 (NP_037519.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MAAA TLTS KLYS LLFR RTST FALT IIVG VMFF ERAF DQGA DAIY DHIN EGKL WKHI KHKY ENK
Gene ID:29796
Uniprot:Q9UDW1
Cellular Location:Mitochondrion inner membrane
Calculated MW:6kDa/7kDa
Observed MW:10kDa
Synonyms:UQCR10, HSPC051, HSPC119, HSPC151, QCR9, UCCR7.2, UCRC
Background:
UniProt Protein Function:UCRC iso3: This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This subunit interacts with cytochrome c1. Belongs to the UQCR10/QCR9 family. The bc1 complex contains 11 subunits: 3 respiratory subunits (cytochrome b, cytochrome c1 and Rieske/UQCRFS1), 2 core proteins (UQCRC1/QCR1 and UQCRC2/QCR2) and 6 low-molecular weight proteins (UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and a cleavage product of Rieske/UQCRFS1).
UniProt Protein Details:

Protein type:Mitochondrial; Energy Metabolism - oxidative phosphorylation

Chromosomal Location of Human Ortholog: 22q12.2

Cellular Component: mitochondrial inner membrane; mitochondrial respiratory chain complex III

Molecular Function:ubiquinol-cytochrome-c reductase activity

Biological Process: cellular metabolic process; mitochondrial electron transport, ubiquinol to cytochrome c

NCBI Summary:UCRC is a subunit of mitochondrial complex III (ubiquinol-cytochrome c reductase; EC 1.10.2.2), which forms the middle segment of the respiratory chain of the inner mitochondrial membrane (Schagger et al., 1995 [PubMed 8592474]).[supplied by OMIM, Mar 2008]
UniProt Code:Q9UDW1
NCBI GenInfo Identifier:9297078
NCBI Gene ID:29796
NCBI Accession:Q9UDW1.3
UniProt Secondary Accession:Q9UDW1,Q9T2V6, B5MCM5,
UniProt Related Accession:Q9UDW1
Molecular Weight:63
NCBI Full Name:Cytochrome b-c1 complex subunit 9
NCBI Synonym Full Names:ubiquinol-cytochrome c reductase, complex III subunit X
NCBI Official Symbol:UQCR10  
NCBI Official Synonym Symbols:QCR9; UCRC; HSPC051; HSPC119; HSPC151; UCCR7.2  
NCBI Protein Information:cytochrome b-c1 complex subunit 9; cytochrome C1, nonheme 7kDa protein; cytochrome c1 non-heme 7 kDa protein; ubiquinol-cytochrome c reductase complex (7.2 kD); ubiquinol-cytochrome c reductase complex 7.2 kDa protein; ubiquinol-cytochrome c reductase, complex III subunit X, 7.2kDa
UniProt Protein Name:Cytochrome b-c1 complex subunit 9
UniProt Synonym Protein Names:Complex III subunit 9; Complex III subunit X; Cytochrome c1 non-heme 7 kDa protein; Ubiquinol-cytochrome c reductase complex 7.2 kDa protein
UniProt Gene Name:UQCR10  
UniProt Entry Name:QCR9_HUMAN
Anti-UQCR10 Antibody (CAB12587)Western blot analysis of extracts of various cell lines, using UQCR10 antibody (CAB12587) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 30s.
Anti-UQCR10 Antibody (CAB12587)Immunohistochemistry of paraffin-embedded rat ovary using UQCR10 antibody (CAB12587) at dilution of 1:100 (40x lens).
Anti-UQCR10 Antibody (CAB12587)Immunohistochemistry of paraffin-embedded rat heart using UQCR10 antibody (CAB12587) at dilution of 1:100 (40x lens).
Anti-UQCR10 Antibody (CAB12587)Confocal immunofluorescence analysis of U2OS cells using UQCR10 Polyclonal Antibody (CAB12587) at dilution of 1:100. Blue: DAPI for nuclear staining.

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