The UTY Polyclonal Antibody (CAB8563) is a vital tool for researchers studying the UTY protein, a member of the H-Y antigen family involved in immune regulation and male-specific functions. This antibody, generated in rabbits, exhibits high specificity and sensitivity for human samples and has been validated for Western blot applications.UTY is known to play a crucial role in immune response modulation, particularly in male-specific immune reactions. Research studies have implicated UTY in conditions such as autoimmune disorders and male infertility, making it a promising target for further investigation.
The UTY Polyclonal Antibody enables researchers to detect and analyze UTY expression in a variety of cell types, facilitating studies in immunology, reproductive biology, and related fields.By gaining a better understanding of UTY's function and regulation, researchers can uncover new insights into immune responses and potentially develop targeted therapies for diseases involving dysregulated immune function. The UTY Polyclonal Antibody is a valuable tool for unraveling the complexities of UTY biology and its implications in health and disease.
Product Name:
UTY Rabbit Polyclonal Antibody
SKU:
CAB8563
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human UTY (NP_009056.3).
This gene encodes a protein containing tetratricopeptide repeats which are thought to be involved in protein-protein interactions. The encoded protein is also a minor histocompatibility antigen which may induce graft rejection of male stem cell grafts. A large number of alternatively spliced transcripts have been observed for this gene, but the full length nature of some of these variants has not been determined.
Purification Method:
Affinity purification
Gene ID:
7404
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using UTY antibody (CAB8563) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.