Description
WDR11 Antibody (CAB10590)
The WDR11 Antibody (CAB10590) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody is raised in rabbits and has been validated for use in a variety of applications, including Western blotting and immunofluorescence. It specifically recognizes the WDR11 protein, allowing for accurate detection and analysis in different cell types.WDR11 is a multifunctional protein involved in various cellular processes, including gene expression regulation and cell cycle progression. Research has shown that WDR11 plays a role in developmental processes and is associated with certain genetic disorders.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
| Product Name: | WDR11 Antibody |
| SKU: | CAB10590 |
| Size: | 20μL, 100μL |
| Reactivity: | Human |
| Conjugate: | Unconjugated |
| Immunogen: | Recombinant protein (or fragment).This information is considered to be commercially sensitive. | ||||
| Sequence: | YFQK FQLE RVNL QEVK RSTY DHTR KCTD QLLL LGQT DRAV QLLL ETSA DNQH YYCD SLKA CLVT TVTS SGPS QSTI KLVA TNMI ANGK LAEG VQLL CLID KAAD ACRY LQTY GEWN RAAW LAKV RLNP EECA DVLR RWVD HLCS PQVN QKSK ALLV LLSL GCFF SVAE TLHS MRYF DRAA LFVE ACLK YGAF EVTE DTEK LITA IYAD YARS LKNL GFKQ GAVL FASK AGAA GKDL LNEL ESPK EEPI EE | ||||
| Tested Applications: | WB ELISA | ||||
| Recommended Dilution: |
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| Synonyms: | DR11, HH14, SRI1, BRWD2, WDR15, WDR11 |
| Positive Sample: | DU145, HL-60, HepG2 |
| Cellular Localization: | Cytoplasm, Membrane, Nucleus, Single-Pass Membrane Protein. |
| Calculated MW: | 137kDa |
| Observed MW: | 130kDa |
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10;19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus.
| Purification Method | Affinity purification |
| Gene ID | 55717 |
| RRID | AB_2758131 |
| Buffer Information | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3. |
 | Western blot analysis of various lysates using WDR11 Rabbit pAb (CAB10590) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s. |
