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Dot-blot analysis of all sorts of peptides using 2'-O-methyluridine(Um) antibody at 1:1000 dilution.
Key Features

2'-O-methyluridine(Um) Monoclonal Antibody (CAB20695)

Datasheet MSDS
SKU CAB20695
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Species independent
Host Species Rabbit
Synonyms Um, 2'-O-methyluridine, 2'-O-methyluridine(Um)
€131 - €457

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Description

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2'-O-methyluridine(Um) Monoclonal Antibody (CAB20695)

The 2'-O-methyluridine(Um) Monoclonal Antibody (CAB20695) is a high-quality antibody developed for reliable detection and analysis of target proteins. This polyclonal antibody, produced in rabbits, specifically targets the 2'-O-Methyluridine (UM) modification, allowing for precise detection and analysis of UM-containing RNA molecules. Validated for use in various applications such as immunoprecipitation and RNA sequencing, this antibody offers high specificity and sensitivity in identifying UM-modified RNAs.The 2'-O-Methyluridine modification is known to play important roles in RNA stability, translation efficiency, and RNA-protein interactions.

This antibody is validated for use in ELISA, DB applications and has demonstrated reactivity against Species independent samples.

Product Name:2'-O-methyluridine(Um) Monoclonal Antibody
SKU:CAB20695
Size:20μL, 100μL
Reactivity:Species independent
Clone Number:ARC50750
Conjugate:Unconjugated
Immunogen:Chemical compounds corresponding to 2'-O-methyluridine(Um).
Sequence:Um c onju gate d to KLH
Tested Applications:ELISA DB
Recommended Dilution:
DB1:500 - 1:1000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:Um, 2'-O-methyluridine, 2'-O-methyluridine(Um)
Observed MW:Refertofigures

Ribose methylation is among the most ubiquitous modifications found in RNA. 2'-O-methyluridine is found in rRNA, snRNA, snoRNA and tRNA of Archaea, Bacteria, and Eukaryota. Moreover, 2'-O-methylribonucleosides are promising starting materials for the production of nucleic acid-based drugs. The chemical modification 2'-O-methyl of nucleosides is often used to increase siRNA stability towards nuclease activities.

Purification MethodAffinity purification
Gene IDCAS: 2140-76-3
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageDot-blot analysis of 2'-O-methyluridine(Um) and unmodified uridine using 2'-O-methyluridine(Um) Rabbit mAb antibody (CAB20695) at 1:1000 dilution. 2'-O-methyluridine : Biotin-5'UGACAACUACAGAC(Um)3' unmodified uridine : Biotin-5'UGACAACUACAGACU3'
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