The ABCA8 Antibody (CAB20553) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, developed using cutting-edge technology, is highly specific to human ABCA8 and has been rigorously tested for use in various applications including immunofluorescence and flow cytometry.ABCA8 is known to play a key role in cellular lipid homeostasis and has been linked to various diseases such as atherosclerosis and metabolic disorders. By targeting ABCA8, researchers can gain valuable insights into the mechanisms underlying lipid-related diseases and potentially identify novel therapeutic targets for intervention.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Rat samples.
Product Name:
ABCA8 Antibody
SKU:
CAB20553
Size:
20μL, 100μL
Reactivity:
Human, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. The encoded protein may regulate lipid metabolism and be involved in the formation and maintenance of myelin. Alternative splicing results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
10351
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using ABCA8 Rabbit pAb (CAB20553) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
