Anti-ABCF1 Antibody (CAB19621)
- SKU:
- CAB19621
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- ABC27
- ABC50
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Product Name: | ABCF1 Rabbit mAb |
| Product Code: | CAB19621 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | ABC27, ABC50 |
| Applications: | WB, IHC |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human ABCF1 |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Rat |
| Positive Samples: | HeLa, HepG2 |
| Immunogen: | A synthesized peptide derived from human ABCF1 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 23 |
| Uniprot: | Q8NE71 |
| Calculated MW: | 96kDa |
| Observed MW: | 120KDa |
| UniProt Protein Function: | ABCF1: Isoform 2 is required for efficient Cap- and IRES- mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis. Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:RNA-binding; Translation Chromosomal Location of Human Ortholog: 6p21.33 Cellular Component: cytoplasm; cytosol; membrane Molecular Function:protein binding; translation factor activity, nucleic acid binding Biological Process: inflammatory response; translation; transmembrane transport |
| NCBI Summary: | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the GCN20 subfamily. Unlike other members of the superfamily, this protein lacks the transmembrane domains which are characteristic of most ABC transporters. This protein may be regulated by tumor necrosis factor-alpha and play a role in enhancement of protein synthesis and the inflammation process. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8NE71 |
| NCBI GenInfo Identifier: | 56417894 |
| NCBI Gene ID: | 23 |
| NCBI Accession: | Q8NE71.2 |
| UniProt Secondary Accession: | Q8NE71,O14897, Q69YP6, A2BF75, |
| UniProt Related Accession: | Q8NE71 |
| Molecular Weight: | 91,680 Da |
| NCBI Full Name: | ATP-binding cassette sub-family F member 1 |
| NCBI Synonym Full Names: | ATP binding cassette subfamily F member 1 |
| NCBI Official Symbol: | ABCF1Â Â |
| NCBI Official Synonym Symbols: | ABC27; ABC50Â Â |
| NCBI Protein Information: | ATP-binding cassette sub-family F member 1 |
| UniProt Protein Name: | ATP-binding cassette sub-family F member 1 |
| UniProt Synonym Protein Names: | ATP-binding cassette 50; TNF-alpha-stimulated ABC protein |
| Protein Family: | ABC transporter F family |
| UniProt Gene Name: | ABCF1Â Â |
| UniProt Entry Name: | ABCF1_HUMAN |
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